Description
Nodular fasciitis is a benign proliferation of fibroblasts and myofibroblasts in the subcutaneous tissues. The lesions are generally small and solitary, arising commonly in the upper extremities of adults and in the head and neck region of infants and children. A history of trauma may precede these reactive lesions, but their cause is unknown.
Physicians are often called upon to do excisional biopsies in the diagnosis of subcutaneous tumors. Benign fibrous tumors represent a group of clinical entities that are often difficult to diagnose. Nodular fasciitis is one such benign fibroblastic proliferation whose rapid growth and rich cellularity frequently cause the lesion to be misdiagnosed as sarcoma.
Nodular fasciitis was first described by Konwaler in 1955 and was termed pseudosarcomatous fibromatosis. Other terms, such as pseudosarcomatous fasciitis, infiltrative fasciitis, and proliferative fasciitis, have also been used synonymously.
The incidence of nodular fasciitis is unknown. It is possible that the lesion's true incidence has been obscured by prior misdiagnosis as malignancy.
Nodular fasciitis is most commonly seen in young adults between 30 and 40 years of age. Approximately 10 percent of the lesions occur in children. Men and women appear equally affected, although in childhood the lesions may occur predominantly in boys.
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