The abscess cavity almost always requires draining. This is done by making a cut in the lining and providing an escape route for the pus, either through a drainage tube or by leaving the cavity open to the skin.
Without spontaneous or surgical drainage, an abscess occasionally resolves slowly after digestion of the pus produces a thin, sterile fluid that is reabsorbed into the bloodstream. Incomplete reabsorbtion leaves a cystic loculation (small pouches) within a fibrous wall where calcium salts sometimes accumulate to form a calcified mass.
Many abscesses subside after drainage alone; others subside after drainage and drug treatment. Occasionally, their presence within a vital organ, such as the liver or brain, damages enough surrounding tissue to cause some permanent loss of normal function.
Antibiotics are usually prescribed to treat a bacterial infection, antifungal drugs to treat fungi, and antiamebic drugs to treat amebiasis. However, the lining of the abscess cavity tends to reduce the amount of drug that can penetrate the source of infection from the bloodstream.
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